News & Events

Events

22 March 2026

High-Affinity 6-letter XenoAptamer

We are excited to announce the online publication of our work in the Journal of the American Chemical Society on high-affinity six-letter DNA  XenoAptamer generation using Ds and Px.

Discoer our latest expetise and innovations from Xenolis R&D team.

 

20 january 2026

Mini-hairpin DNA

We are pleased to announce a review article by our CSO, Dr. Ichiro Hirao, and COO, Dr. Michiko Kimoto, published in Chemistry – A European Journal.

 

Discover the fascinating background story behind the discovery of mini-hairpin DNA—an extraordinarily stable, compact DNA structure—and explore how this short sequence has been applied to modern nucleic acid engineering and biotechnology.

16 December 2025

Two Bases, Big Impact

 

Two unnatural bases unlock high-affinity, high-specificity XenoAptamers.

  • Ds expands structural diversity for optimal binding.
  • Px/Pa′ directly strengthens interactions with target proteins.
  • Together, they form a rigid, high-performance structure

Small atomic changes, major gains in affinity.

 

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