Advancing Life Sciences via Genetic Alphabet Expansion

Xenolis Pte. Ltd. is a deep technology platform company that applies its proprietary synthetic DNA bases to develop highly customized XenoAptamer™ that can be applied across research and discovery.

OUR COMPANY

About Us

Xenolis Pte Ltd is a life sciences company that specializes in the discovery and development of XenoAptamers for use in life sciences application and research. XenoAptamers are advanced aptamers that contain proprietary unnatural bases and have unique properties and configurations. This allows us to produce aptamers with high affinity and specificity to their targets, making them ideal for broad applications across life sciences.

Xenolis’ proprietary ExSELEX™ platform is a transformative and agnostic technology that impacts multiple sectors of the life science industry via genetic alphabet expansion. This platform extends its utility from research and discovery, translational research and biopharmaceutical development, and clinical applications.

Our Science

Technology

XenoAptamers

Xenolis’ new XenoAptamers, short single-stranded DNA or RNA with our proprietary unnatural bases

The ExSELEX™ Platform

We developed our proprietary technique called ExSELEX (genetic alphabet Expansion for Systematic Evolution

Six-Letter DNA Alphabet

We have developed an unnatural base pair system for six-letter PCR in ExSELEX.

Genetic Alphabet Expansion Technology

Introducing Xenolis, where innovation meets precision. With our proprietary artificial base pairs (Ds−Px and Ds−Pa)

Genetic Alphabet Expansion Technology

Introducing Xenolis, where innovation meets precision. With our proprietary artificial base pairs (Ds−Px and Ds−Pa), we are crafting novel nucleic acids like XenoAptamers and more.

Step into genetic innovation’s future with our cutting-edge genetic alphabet expansion technology! By harnessing artificially created third base pairs (unnatural base pairs), we are transforming traditional 4-letter DNA into groundbreaking 6-letter DNA. 

Products & Services

Our WOrk Flow

01

CHARACTERISATION

The candidates identified are synthesized and evaluated with respect to affinity and specificity of interaction with the target, using Surface Plasmon Resonance (SPR).

02

FEASIBILTY STUDY

An in-depth discussion with the client to define their needs, requirements and objectives and setup milestones to meet their goals.

03

SELECTION

Selection of aptamers against selected targets using our proprietary DNA libraries. Iterative steps of selection and amplification over a few rounds under increasing stringency.

Reach Out To Us

If you need further information or you interested in getting a customised XenoAptamer for your application, we will be pleased to help.

Reach Out To Us

If you need further information or you interested in getting a customised XenoAptamer for your application, we will be pleased to help.
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