Revolutionizing Life Sciences with Advanced Genetic Tools and Customized XenoAptamers™ via Advanced SELEX Techniques
Xenolis Pte. Ltd. is a deep technology platform company that applies its proprietary synthetic DNA bases to develop highly customized XenoAptamer™ that can be applied across research and discovery.
Explore our range of XenoAptamers and affinity rulers, all crafted using modified nucleotides and advanced SELEX technology to ensure superior performance in DNA/RNA engineering.
Stay updated with our latest advancements in aptamer technology and SELEX research through our presentations.
OUR COMPANY
About Us
At Xenolis Pte Ltd, we specialize in pioneering the discovery and development of aptamers, through our advanced SELEX technology, particularly focusing on our innovative XenoAptamers™. These aptamers, enhanced with proprietary unnatural bases, are designed to significantly advance life sciences research and applications. XenoAptamers, our specialized aptamers, feature innovative unnatural bases that provide unparalleled specificity and affinity for their targets, enhancing various life science applications.
Our ExSELEX™ platform not only utilizes tranditional SELEX methods but also introduces modifications at the genetic level, creating aptamers through a sophisticated six-letter DNA alphabet system. This advanced technology allows for the creation of highly specific and functional aptamers that outperform traditional biomolecules.
Our Science
Technology
XenoAptamers
Xenolis’ new XenoAptamers, short single-stranded DNA or RNA with our proprietary unnatural bases
The ExSELEX™ Platform
We developed our proprietary technique called ExSELEX (genetic alphabet Expansion for Systematic Evolution
Six-Letter DNA Alphabet
We have developed an unnatural base pair system for six-letter PCR in ExSELEX.
Genetic Alphabet Expansion Technology
Introducing Xenolis, where innovation meets precision. With our proprietary artificial base pairs (Ds−Px and Ds−Pa)
Genetic Alphabet Expansion Technology
Introducing Xenolis, where innovation meets precision. With our proprietary artificial base pairs (Ds−Px and Ds−Pa), we are crafting novel nucleic acids like XenoAptamers and more.
Step into genetic innovation's future with our cutting-edge genetic alphabet expansion technology! By harnessing artificially created third base pairs (unnatural base pairs), we are transforming traditional 4-letter DNA into groundbreaking 6-letter DNA.
Products & Services
Our Work Flow
01
CHARACTERISATION
The candidates identified are synthesized and evaluated with respect to affinity and specificity of interaction with the target, using Surface Plasmon Resonance (SPR).
02
FEASIBILTY STUDY
An in-depth discussion with the client to define their needs, requirements and objectives and setup milestones to meet their goals.
03
SELECTION
Selection of aptamers against selected targets using our proprietary DNA libraries. Iterative steps of selection and amplification over a few rounds under increasing stringency.
Reach Out To Us
If you're looking to harness the power of custom-designed aptamers in your research or applications, reach out to explore how our tailored XenoAptamers can meet your needs.